Tomography, Optical Coherence
My main research focus is to advance optical coherence tomography (OCT), for high speed and high resolution imaging of the human retina. I therefore use a line field OCT approach to parallelize one dimension. This should enable us high resolution imaging on a cellular level without the use of hardware bases adaptive optics.
Techniques, methods & infrastructure
The main technique is of course OCT at 800 and 1060nm. Using spectrometer based systems as well as swept source system, even time domain is used as one approach.
- L. Ginner, A. Kumar, D. Fechtig, L. Wurster, M. Salas, M. Pircher, and R. Leitgeb, "Noniterative digital aberration correction for cellular resolution retinal optical coherence tomography in vivo," Optica 4, 924-931 (2017).
- Ginner, L. et al. Wide-Field OCT Angiography at 400 KHz Utilizing Spectral Splitting. Photonics 1, 369,
- Ginner, L. et al., 2018. Holographic line field en-face OCT with digital adaptive optics in the retina in vivo. Biomedical Optics Express, 9(2), p.472. Available at: http://dx.doi.org/10.1364/BOE.9.000472.
- L. Ginner, A. Wartak, M. Salas, M. Augustin, M. Niederleithner, L. M. Wurster, R. A. Leitgeb, “Synthetic subaperture-based angle-independent Doppler flow measurements using single-beam line field optical coherence tomography in vivo “,Optics Letters Vol. 4, No. 4 967-790 (2019)