- Regional and Paediatric Anaesthesia
My main research focus is regional anaesthesia and paediatric anaesthesia. Our study group initiated the use of ultrasound for regional anaesthesia purposes, and since that time we established these techniques worldwide. Regional anaesthesia became safer and more practicable with the use of ultrasound.
Techniques, methods & infrastructure
The cooperation with the Department of Clinical Pharmacology enables volunteer studies in the field of regional anaesthesia. Data from these studies are exact and can be transferred in the daily clinical practice. We perform pharmacodynamic and pharmacokinetic clinical studies in adult volunteers. Studies with paediatric populations can be only performed in the OR, and we are able to answer various clinical questions with highest ethical and scientific standards.
- Keplinger, M. et al., 2015. A pharmacodynamic evaluation of dexmedetomidine as an additive drug to ropivacaine for peripheral nerve blockade. European Journal of Anaesthesiology, 32(11), pp.790-796. Available at: http://dx.doi.org/10.1097/EJA.0000000000000246.
- Kessler, J. et al., 2015. Peripheral regional anaesthesia and outcome: lessons learned from the last 10 years J. G. Hardman, ed. Br. J. Anaesth., 114(5), pp.728-745. Available at: http://dx.doi.org/10.1093/bja/aeu559.
- Marhofer, D. et al., 2013. Dislocation rates of perineural catheters: a volunteer study. British Journal of Anaesthesia, 111(5), pp.800-806. Available at: http://dx.doi.org/10.1093/bja/aet198.
- Marhofer, D. et al., 2013. Magnetic Resonance Imaging Analysis of the Spread of Local Anesthetic Solution after Ultrasound-guided Lateral Thoracic Paravertebral Blockade. Anesthesiology, 118(5), pp.1106-1112. Available at: http://dx.doi.org/10.1097/ALN.0b013e318289465f.
- Marhofer, P. et al., 2013. Ultrasound-guided peripheral regional anaesthesia: a feasibility study in obese versus normal-weight women. International Journal of Obesity, 38(3), pp.451-455. Available at: http://dx.doi.org/10.1038/ijo.2013.119.