NECAB2 is a Ca2+ binding protein involved in striatal function
Professor of Neurology, Head of the section acute neurology
Forschungszentrum Translationale Neurowissenschaften University of Mainz, Department of Neurology
Host: M. Freissmuth / K. Nowikovsky
Axel Methner is Professor of Neurology and Head of the section Acute Neurology at the Johannes Gutenberg University Medical Center Mainz. Besides clinical work, he heads a research lab that is part of the Focus program Translational Neuroscience (FTN) at the Johannes Gutenberg University Mainz. The research goal of the Methner lab is to understand how neuronal cell death occurs and how to prevent it. His laboratory studies the mechanisms of resistance against oxidative stress, the role of the calcium machinery in cell death and protection, and transcriptional effectors of cell survival in models of neurological disease by employing a combination of molecular and cell biological, biochemical, and genetic approaches using neurons and neuronal stem cells in primary culture.