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MIC – Lecture: "Non-invasive imaging of neurochemistry via Magnetic Resonance imaging”


17. Oktober 2018
13:00 - 15:00

Pokieser-Seminarraum, 7 F, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna

Assoc. Prof. PD Dr Wolfgang Bogner (High-field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Innsbruck)

Many neurological and psychiatric disorders benefit significantly from the exquisite soft-tissue contrast of magnetic resonance imaging techniques, but conventional MRI contrasts are limited to the mapping of macro-/microscopic tissue properties. Neurochemical MRI methods such as MR spectroscopic imaging or Chemical Exchange Saturation Transfer MRI are sensitive to alterations in various chemical compounds in the brain including markers for neuronal integrity, cell energy metabolism, cell proliferation, neurotransmission, and oxidative stress. These neurochemical alterations are not only fundamental to the pathogenesis of many disorders; they are also frequently preceding macroscopically visible changes as seen by conventional MRI. This makes neurochemical MRI a powerful tool for clinical studies that aim for a better understanding of the pathophysiological underpinnings of central nervous system disorders.  

Wolfgang Bogner, PhD
Associate Professor/Habilitation for Medical Physics
High-field MR Center, Department of Biomedical Imaging and Image-guided Therapy
Medical University of Vienna, Austria

Wolfgang Bogner is a physicist and leads a research group on molecular MR imaging at the High-field MR Center. He has specialized on the development of new neurochemical MR imaging methods, in particular at ultra-high magnetic field, and the translation of these new techniques into the clinical environment. He earned his doctorate in Technical Physics at the Technical University of Vienna in 2009 (in collaboration with the Medical University Vienna) and habilitated in Medical Physics at the Medical University of Vienna in 2017. Via an Erwin Schrödinger Stipend he worked at the Martinos Center, MGH/Harvard Medical School in 2012/2013 before he was appointed Associate Professor at the Medical University Vienna in 2014.

The main areas of research are the development of image acquisition and reconstruction methods for high-field MRI including in particular accelerated data sampling, real-time motion correction, multi-parametric MRI, and neurochemical MRI.