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Lukas Kenner
Prof. Dr. Lukas Kenner

Department of Pathology
Position: Professor

ORCID: 0000-0003-2184-1338
T +43 1 40400 36590


Prostate; Transcription Factor AP-1; Translational Medical Research

Research interests

  • AP-1 and JAK-STAT signaling and core cancer pathways
  • Basic and translational cancer research with a main focus on comparative pathology in human patient samples compared to gene targeted mouse models to explore new diagnostic approaches facilitating digital pathology procedures for establishing new therapies

Techniques, methods & infrastructure

Tissue micro arrays (TMA) of human patient samples, digital pathology, laboratory animal and translational pathology, transgenic mouse modelling, patient-derived grafts (PDX), organoid-derived grafts (ODX), CRISPR-Cas9, RNA knock-down strategies. 

Molecular pathology methods (protein DNA and RNA analysis), in-vitro cell culture methods.


Selected publications

  1. Pencik, J. et al., 2015. STAT3 regulated ARF expression suppresses prostate cancer metastasis. Nature Communications, 6, p.7736. Available at:
  2. Merkel, O. et al., 2015. Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation. The Journal of Pathology, 236(4), pp.445-456. Available at:
  3. Laimer, D. et al., 2012. PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas. Nature Medicine, 18(11), pp.1699-1704. Available at:
  4. Merkel, O. et al., 2010. Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma. Proceedings of the National Academy of Sciences, 107(37), pp.16228-16233. Available at:
  5. Pflegerl, P. et al., 2009. Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling. Proceedings of the National Academy of Sciences, 106(48), pp.20423-20428. Available at: