Detail

Keywords

Immune System; Microbiology; Oncology; Urinary Bladder

Research group(s)

• Research Lab Urology
  Head: Shahrokh F. Shariat
  Members:
  Ursula Lemberger

Research interests

My research focuses on urologic oncology – especially on molecular mechanisms and markers to improve diagnostics and prognostics in upper tract and urothelial bladder cancer. Moreover, I am investigating tumor immunology, the urogenital microbiome and its impact on chronic inflammation, stone formation and tumorigenesis.

Techniques, methods & infrastructure

 Our lab is well equipped to complete standard DNA, RNA and protein expression analysis. Moreover, we perform Next Generation Sequencing and drug screening on patient derived tumor cell lines.  

Selected publications

1. Lemberger, U.J. et al., 2018. Hepatocyte specific expression of an oncogenic variant of β-catenin results in lethal metabolic dysfunction in mice. Oncotarget, 9(13). Available at: http://dx.doi.org/10.18632/oncotarget.24346.
2. Lemberger, U.J. et al., 2016. Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease. Oncotarget, 7(52). Available at: http://dx.doi.org/10.18632/oncotarget.13521.
3. Kantari-Mimoun, C. et al., 2017. Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice. Oncotarget, 8(9). Available at: http://dx.doi.org/10.18632/oncotarget.14749.