Detail

Keywords

Anti-Infective Agents; Pharmacokinetics

Research group(s)

• Section of Clinical Pharmacokinetics / Pharmacogenetics and Imaging
  Head: Markus Zeitlinger
  Research Area: Our main focus is the study of the drug distribution process by employing techniques to measure target site distribution directly, i.e. PET or microdialysis.
  Members:
  Valentin al Jalali
  Severin Mairinger
  Alina Nussbaumer-Pröll
  Iris Minichmayr
  Anselm Jorda
  Oliver Langer

Research interests

Clinical and tissue pharmacokinetics, study design, anti-infectives, human inflammation models

Selected publications

1. Jorda, A. et al. (2025) ‘Stability of cytokine, cellular and clinical response to the intravenous LPS challenge repeated after one year: a healthy volunteer trial’, Medical Microbiology and Immunology, 214(1). Available at: https://doi.org/10.1007/s00430-025-00823-5.
2. Gelbenegger, G. et al. (2025) ‘Lactated Ringer’s or Normal Saline for Initial Fluid Resuscitation in Sepsis-Induced Hypotension’, Critical Care Medicine, 53(5), pp. e1140–e1144. Available at: https://doi.org/10.1097/ccm.0000000000006601.
3. Gelbenegger, G. et al. (2025) ‘Amiodarone dose in patients with shockable out-of-hospital cardiac arrest’, Resuscitation, 209, p. 110534. Available at: https://doi.org/10.1016/j.resuscitation.2025.110534.
4. Jorda, A. et al. (2025) ‘Immunogenicity, safety, and reactogenicity of concomitant administration of the novavax vaccine against Omicron XBB.1.5 (NVX-CoV2601) and a 20-valent pneumococcal conjugate vaccine in adults aged ≥60 years: A randomised, double-blind, placebo-controlled, non-inferiority trial’, Journal of Infection, 90(2), p. 106405. Available at: https://doi.org/10.1016/j.jinf.2024.106405.
5. Jorda, A. et al. (2025) ‘Real-world effectiveness of nirmatrelvir-ritonavir and molnupiravir in non-hospitalized adults with COVID-19: a population-based, retrospective cohort study’, Clinical Microbiology and Infection, 31(3), pp. 451–458. Available at: https://doi.org/10.1016/j.cmi.2024.10.026.