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Detail

Lukas Weseslindtner
Ass.Prof.Priv.Doz.Dr.med. Lukas Weseslindtner

Center for Virology
Position: Assistant Professor

T +43 1 40160 65509
lukas.weseslindtner@meduniwien.ac.at

Keywords

Chemokines; Clinical virology ; T Cells

Research group(s)

  • T-cell responses and T-cell associated chemokines in clinical virology
    Members:

Research interests

Antiviral T-cell responses and chemokines that attract T-cells to the site of the infection are essential for an efficient control of viral replication. The aim of my research is to investigate whether antiviral T-cell responses and T-cell associated chemokines may serve as clinical markers to evaluate the stage, course and severity of different virus infections.  
 

Techniques, methods & infrastructure

  • Fluorescent Activated Cell Sorter Analysis,
  • Standardized T-cell assays (i.e. QuantiFERON-assay),
  • Quantitative chemokine ELISAs

Selected publications

  1. Weseslindtner L et al. Intrapulmonary Human Cytomegalovirus replication in lung transplant recipients is associated with a rise of CCL-18 and CCL-20 chemokine levels. Transplantation. 2016; in press
  2. Weseslindtner L et al. High CXCL-16 Levels Correlate With Symptomatic Disease in Lung Transplant Recipients With Human Cytomegalovirus Replication in the Allograft. Am J Transplant. 2014; 14: 2406-11.
  3. Weseslindtner L et al. Prospective Analysis of Human Cytomegalovirus DNAemia and Specific CD8+ T-Cell Responses in Lung Transplant Recipients. Am J Transplant. 2012; 12:2172-80.
  4. Weseslindtner L et al. Human cytomegalovirus infection in lung transplant recipients triggers a CXCL-10 response. Am J Transplant. 2011; 11:542-52.
  5. Weseslindtner L et al. Acute infection with a single hepatitis C virus strain in dialysis patients: Analysis of adaptive immune response and viral variability. J Hepatol. 2009; 50:693-704.