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Detail

Michael Leutner
Dr. Michael Leutner, MSc PhD

Department of Medicine III (Division of Endocrinology and Metabolism)
Position: Doctor-in-training

ORCID: 0000-0003-3959-1496
T +43 1 40400 22290
michael.leutner@meduniwien.ac.at

Keywords

Diabetes Mellitus; Diabetes, Gestational; Dyslipidemias; Endocrinology; Glucose Metabolism Disorders; Osteoporosis

Research interests

My current research investigates the relationship between cholesterol-lowering drugs such as statins and the development of hormone-related diseases. Statins inhibit HMG-CoA reductase, the main enzyme in the synthesis of cholesterol. Cholesterol is the basic substance for the synthesis of vital hormones such as testosterone or oestrogen. I am therefore currently investigating whether there is a dose-dependent relationship between statins and osteoporosis.

Further research interests are:

  • Endocrinology and metabolism
  • Hyperlipidemia
  • Diabetes mellitus
  • Gender Medicine
  • Gestational diabetes

Techniques, methods & infrastructure

  • Big data
  • Prospective clinical studies
  • Functional tests measuring insulin secretion, insulin sensitivity, beta-cell function and incretins
  • Continuous glucose monitoring
  • Magnetic resonance spectroscopy
  • Intestinal microbiome 

Selected publications

  1. Leutner, M et al, 2019. Diagnosis of osteoporosis in statin-treated patients is dose-dependent. Ann Rheum Dis. 2019 Dec;78(12):1706-1711.
  2. Leutner, M et al, 2019. A Sex-Specific Analysis of the Predictive Value of Troponin I and T in Patients With and Without Diabetes Mellitus After Successful Coronary Intervention. Front Endocrinol (Lausanne). 2019 Mar 1;10:105.
  3. Leutner, M et al, 2019. Glucagon-like peptide 1 (GLP-1) drives postprandial hyperinsulinemic hypoglycemia in pregnant women with a history of Roux-en-Y gastric bypass operation. Metabolism. 2019 Feb;91:10-17.
  4. Leutner, M et al, 2018. Pericardial Fat Relates to Disturbances of Glucose Metabolism in Women with the Polycystic Ovary Syndrome, but Not in Healthy Control Subjects. Int J Endocrinol. 2018 Aug 7;2018:5406128.
  5. Leutner, M et al, 2016. Clinical and metabolic characteristics of treated hyperlipidemic patients additionally affected by subclinical hyperglycemia. Lipids Health Dis. 2016 Jan 13;15:10.
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