Models, Statistical; Multivariate Analysis; Outcome Assessment (Health Care); Patient Outcome Assessment; Principal Component Analysis
We analyse outcome data in health care, develop corresponding instruments, optimize measurement scales and adapt assessments to different contexts. Outcomes include the measurement of clinical signs and symptoms as well as results of medical interventions, but also quality of life, functioning, pain, fatigue or the impact of exercise-induced dyspnoea in daily life - outcomes which are most important for patients. In people with acute and chronic health conditions of the cardiovascular system, other internal organs or the musculoskeletal system, in children, in older adults and in rehabilitation, it is essential to include the perspective of patients into outcome measurement.
Techniques, methods & infrastructure
The Section for Outcomes Research develops methods to measure, analyse and compare outcomes in health care by using complex scores, patient-reported instruments, multivariate models, Rasch analyses, mixed methods, and activity- and motion-analyses. Data gathering is optimized with sensor technologies and e-health solutions. Furthermore, qualitative research methods are developed and applied.
- Omara, M. et al., 2019. Rasch model of the Child Perceptions Questionnaire for oral health–related quality of life. The Journal of the American Dental Association. Available at: http://dx.doi.org/10.1016/j.adaj.2018.12.001.
- Stamm, T.A. et al., 2018. Induction of sustained remission in early inflammatory arthritis with the combination of infliximab plus methotrexate: the DINORA trial. Arthritis Research & Therapy, 20(1). Available at: http://dx.doi.org/10.1186/s13075-018-1667-z.
- Stoffer-Marx, M.A. et al., 2018. Functional consultation and exercises improve grip strength in osteoarthritis of the hand – a randomised controlled trial. Arthritis Research & Therapy, 20(1). Available at: http://dx.doi.org/10.1186/s13075-018-1747-0.
- Dür, M. et al., 2016. Initial evidence for the link between activities and health: Associations between a balance of activities, functioning and serum levels of cytokines and C-reactive protein. Psychoneuroendocrinology, 65, pp.138–148. Available at: http://dx.doi.org/10.1016/j.psyneuen.2015.12.015.
- Stamm, T.A. et al., 2011. Concepts of functioning and health important to people with systemic sclerosis: a qualitative study in four European countries. Annals of the Rheumatic Diseases, 70(6), pp.1074–1079. Available at: http://dx.doi.org/10.1136/ard.2010.148767.