Biofilms; Bone Diseases, Infectious; Candidiasis, Invasive; Drug Resistance, Microbial; Endocarditis; Hand Hygiene; Hygiene
- Bone Research
- Infection Control and Hospital Epidemiology
The microbiological research focuses on microbial biofilms, biofilm- and implant-associated infections (prosthetic joint infections, endocarditis) and biofilm formation factors for early diagnosis and treatment.
Further research focuses on epidemiology, prevention and control of healthcare-associated infections (HAI) and multi-resistant bacteria genotyping of the latter. We do studies for applied hospital hygiene and intervention studies. A continuous interest is in the epidemiology, clinical course, control and prevention of invasive fungal infections.
Techniques, methods & infrastructure
- Biofilm models (static, dynamic), staining and quantifying of biofilms, fluorescent stains, confocal laser scanning microscopy (together with the imaging core unit), resistance testing of biofilms;
- Intervention studies, environmental cultures for applied hospital studies; epidemiology
- Holinka, J. et al., 2010. Sonication cultures of explanted components as an add-on test to routinely conducted microbiological diagnostics improve pathogen detection. Journal of Orthopaedic Research, 29(4), pp.617-622. Available at: http://dx.doi.org/10.1002/jor.21286.
- Presterl, E. et al., 2009. Effects of Azithromycin in Combination with Vancomycin, Daptomycin, Fosfomycin, Tigecycline, and Ceftriaxone on Staphylococcus epidermidis Biofilms. Antimicrobial Agents and Chemotherapy, 53(8), pp.3205-3210. Available at: http://dx.doi.org/10.1128/AAC.01628-08.
- Forstner, C. et al., 2015. Non-linear significant relationship between use of glycopeptides and isolation of vancomycin-resistant Enterococcus species in a university hospital setting. Antimicrobial Resistance and Infection Control, 4(1). Available at: http://dx.doi.org/10.1186/s13756-015-0064-5.
- Forstner, C. et al., 2013. A prospective analysis of invasive candidiasis following cardiac surgery: Severity markers are predictive. Journal of Infection, 66(6), pp.528-535. Available at: http://dx.doi.org/10.1016/j.jinf.2013.02.003.
- Fochtmann, A. et al., 2015. Clinical significance of Candida colonization of central vascular catheters in patients with major burns requiring intensive care. Intensive Care Medicine, 41(6), pp.1143-1144. Available at: http://dx.doi.org/10.1007/s00134-015-3784-3.