Medical Physics; Optical Imaging; Tomography, Optical Coherence
Principal fields of research: Biomedical Optics. Low coherence interferometry (LCI) and optical coherence tomography (OCT). Pioneering work in these fields since 1987.
Major contributions to these fields: Introduction of the optical A-scan (heterodyne LCI) for in vivo intraocular ranging (this “optical A-scan” is a one-dimensional image and forms the basic element of an OCT scan); measurements of intraocular distances in humans in vivo (1990); in vivo OCT tomogram of a human retina (1993); numerous applications of LCI in cataract patients (since 1993); participation in the development of the LCI-based "IOL-Master" (Carl Zeiss, Inc.). First demonstration of Spectral Domain (SD) OCT principle (1995); first demonstration of sensitivity advantage of SD OCT (2003).
Main research interests at present: Contrast enhancement and generation techniques in OCT, polarization sensitive OCT, Doppler OCT, multidirectional OCT, ophthalmic imaging.
Techniques, methods & infrastructure
Development of advanced OCT techniques and demonstration in the healthy and diseased eye. Available prototype instruments: various polarization sensitive OCT sytems, multibeam Doppler OCT, multidirectional OCT.