Aneurysm, Ruptured; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Biomarkers, Pharmacological; Cardiovascular Abnormalities; Cardiovascular Diseases; Cardiovascular System; Carotid Artery Diseases; General Surgery; Glomerular Filtration Rate; Kidney Failure, Chronic; Kidney Function Tests; Molecular Biology; Monocytes; Neutrophils; Randomized Controlled Trial
- Arge Brostjan
Research Area: Vascular Disease
- Vienna Vascular Surgery Research Laboratories
My main research focus is to investigate biomarkers and inflammatory components in cardiovascular and associated diseases, especially focused on translational research regarding neutrophils and neutrophil extracellular traps (NETs) in abdominal aortic aneurysms (AAAs).
We perform different mouse models of AAA and the research is designed to elucidate molecular mechanisms of cardiovascular disease underlying different aspects of pathology and to develop novel therapeutic approaches.
In addition, I am involved in randomized clinical trials and biobanking at the Department of Surgery - Division of Vascular Surgery at the Medical University of Vienna, Vienna General Hospital.
- Award Winner of the Austrian Society of Surgery 2020
- Member of the International Society of Surgery
- Member of the Austrian Society of Vascular Surgery
- Member of the Austrian Society of Surgical Research
- Member of the Austrian Society of Surgery
- Zagrapan, B. et al., 2019. A Novel Diagnostic and Prognostic Score for Abdominal Aortic Aneurysms Based on D-Dimer and a Comprehensive Analysis of Myeloid Cell Parameters. Thrombosis and Haemostasis, 119(05), pp.807–820. Available at: http://dx.doi.org/10.1055/s-0039-1679939.
- Klopf, J., et al., Strategies so far and future Prospects for Reducing Growth Rates in abdominal Aortic Aneurysms A selective Literature Review and Discussion of the current Vienna MetAAA Trial. Gefasschirurgie, 2020. 25(6): p. 446-449.