Univ.-Prof. Dipl.-Ing. Dr.techn. Wolfgang DrexlerHead of Center for Medical Physics and Biomedical Engineering, Honorary Distinguished Professor Cardiff University, UK
Center for Medical Physics and Biomedical Engineering
Position: Professor
T +43 1 40400 19860
wolfgang.drexler@meduniwien.ac.at
Keywords
Endoscopy; Microscopy; Molecular Imaging; Nanotechnology; Optical Imaging; Photoacoustic Techniques; Tomography, Optical Coherence
Research group(s)
- Leitgeb & Drexler Group
Research Area: Advancing biomedical optical imaging for a step change in medical diagnostics as well as in fundamental biological and medical research by developing cutting edge optical technologies combining strengths of different imaging modalities.
Members:
Research interests
- Translational multimodal optical imaging (OCT, MPM, CARS, SRS, Raman, photo acoustics, adaptive optics)
- Molecular contrast optical imaging (endogenous and exogenous contrast agents)
- Multimodal optical endoscopy (incl. cystoscopy, laparoscopy, tethered capsule, needle etc.)
- Intraoperative multimodal optical imaging (incl. eye, brain) – non-invasive therapy monitoring
- Biophotonics (incl. semiconductor, fiber based and ultrafast pulse laser technology)
- Nanophotonics - Photonics integrated circuit (PIC) based imaging and sensing (OCT on a chip, lab on a chip)
Techniques, methods & infrastructure
- State of the art optical imaging laboratories with actively damped optical tables, optical analysis and test equipment
- Numerous OCT, microscopy, spectroscopy and optical endoscopy (probe) systems
- Ultrashort pulse laser technology (Titanium:sapphire laser, OPO) dye laser, fiber (PCF) based laser technology
- Akinetic and commercial swept source laser technology at various wavelengths
- Two clean rooms (class 1000 and class 100), a chemical lab, a dedicated mechanical workshop, plastic lab as well as state of the art additive manufacturing (3D printing) are available in the Center
Grants
- REAP (2021)
Source of Funding: EU, H2020 - ICT - 101016964
Coordinator of the collaborative project - HandheldOCT (2020)
Source of Funding: EU, H2020-ICT-2019-2, 871312
Coordinator of the collaborative project - PHAST (2020)
Source of Funding: EU, H2020-MSCA-ITN-2019
Principal Investigator - PROSCOPE (2020)
Source of Funding: EU, H2020-ICT-2019-2, 871212
Principal Investigator - SWIMMOT (2020)
Source of Funding: EU, H2020 - FETOPEN 899612
Principal Investigator - Tomography across the Scales (project part leader) (2017)
Source of Funding: FWF (Austrian Science Fund), Special Research Programmes (SFB68)
Principal Investigator - Hybrid optical and optoacoustic endoscope for esophageal tracking, ESOTRAC (2016)
Source of Funding: EU, H2020-ICT-2016-1
Principal Investigator - Multi-modal, Endoscopic Biophotonic Imaging of Bladder Cancer for Point-of-Care Diagnosis - MIB (2016)
Source of Funding: EU, H2020-PHC-2015-two-stage
Principal Investigator - Ophthalmic OCT on a Chip, OCTCHIP (2016)
Source of Funding: EU, H2020-ICT-2015
Coordinator of the collaborative project
Selected publications
- Leitgeb, R. et al., 2021. Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography. Journal of Biomedical Optics, 26(10). Available at: http://dx.doi.org/10.1117/1.JBO.26.10.100601.
- Rank, E.A. et al., 2021. Toward optical coherence tomography on a chip: in vivo three-dimensional human retinal imaging using photonic integrated circuit-based arrayed waveguide gratings. Light: Science & Applications, 10(1). Available at: http://dx.doi.org/10.1038/s41377-020-00450-0.
- W. Drexler, J.G. Fujimoto, 2015. Optical Coherence Tomography: Technology and Applications, 2nd edition, Springer International Publishing Switzerland, 3 Volumes, 2571 pages, 337 b/w illustrations, 1104 illustrations in colour, ISBN 978-3-319-06420-8
- Bizheva, K. et al., 2006. Optophysiology: Depth-resolved probing of retinal physiology with functional ultrahigh-resolution optical coherence tomography. Proceedings of the National Academy of Sciences, 103(13), pp.5066–5071. Available at: http://dx.doi.org/10.1073/pnas.0506997103.
- Drexler, W. et al., 2001. Ultrahigh-resolution ophthalmic optical coherence tomography. Nature Medicine, 7(4), pp.502-507. Available at: http://dx.doi.org/10.1038/86589.