Department of Biomedical Imaging and Image-guided Therapy (Division of Nuclear Medicine)
Position: Research Assistant
ORCID: 0009-0007-6656-1088
T +43 1 40400 55640
maximilian.krisch@meduniwien.ac.at
Keywords
Drug Evaluation, Preclinical; Fluorine Radioisotopes; Metabolic Networks and Pathways; Molecular Imaging; Neuroimaging; Positron-Emission Tomography; Radioactive Tracers; Stress, Physiological
Research group(s)
- Experimental Nuclear Medicine
Head: Cécile Philippe
Research Area: The research group "Experimental Nuclear Medicine" deals with the development and evaluation of radiotracers in various diseases. In addition, the group focuses on organ axes and pharmacokinetics.
Members: - Translational Chronic Mental Stress (Vraka Group)
Head: Chrysoula Vraka
Research Area: Chronic mental stress is a key but underrecognized risk factor for metabolic and inflammatory disorders, contributing to diseases like CVD, depression, neurodegeneration, and cancer. Stress alters metabolism via cortisol, promoting insulin resistance and fat storage. PET biomarkers enable insight into stress-inflammation links. We aim for a bidirectional mouse-human translational pipeline to uncover mechanisms and support preventive strategies.
Members:
Research interests
The research topic of my PhD revolves around stress response including its effects on metabolism and health. By establishing preclinical stress protocols and employing a variety of methods like µPET/CT-Imaging, Immunoassays, Omics, FACS, etc., I aim to gain further insight into this complex topic and help to understand how stress affects our body.
Techniques, methods & infrastructure
- Preclinicial Imaging µPET/CT & µPET/MR
- Stress Models (Cold, Restraint, Surgery, CVS)
- Image Analysis (πPMOD, SPM)
- ex-vivo Biodistribution Studies
- Radiochemistry (18F-labeling)
- (Bio)analytical Methods (ELISA, qPCR, HPLC, LC/MS, AURA, Histology...)