Skip to main content

Detail

Marius Ozenil
Marius Ozenil, MSc

Department of Biomedical Imaging and Image-guided Therapy (Division of Nuclear Medicine)
Position: PHD Student

ORCID: 0000-0001-6369-6613
T +43 1 40400 78350
marius.ozenil@meduniwien.ac.at

Keywords

Positron-Emission Tomography; Radiochemistry

Research interests

My PhD thesis focuses on the development of PET tracers for neuroimaging of muscarinic acetylcholine receptors. Chemical derivatization of known mAChR ligands allows to tune suitable pharmacological properties for tracer development. Radiochemical labeling of tracers is performed with cyclotron produced radionuclides (11C, 18F) and parameters like ligand receptor kinetics, lipophilicity, plasma protein binding and metabolic stability are assessed.

Techniques, methods & infrastructure

Synthetic chemistry (organic and inorganic), analytical chemistry and structure identification (NMR, MS and other spectroscopic methods), chromatography (especially HPLC), radiochemistry of PET nuclides (11C, 18F)