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Cécile Philippe
Ap. Prof. Mag. Dr. Cécile PhilippeGroup Leader Experimental Nuclear Medicine

Department of Biomedical Imaging and Image-guided Therapy (Division of Nuclear Medicine)
Position: Associate Professor

ORCID: 0000-0002-7203-7174
T +43 1 40400 20340

Further Information


Drug Evaluation, Preclinical; Molecular Imaging; Positron-Emission Tomography; Radioactive Tracers

Research interests

Biomedical Imaging and Tracer Development

My main area of research is the preclinical development and evaluation of radiopharmaceuticals with focus on energy metabolism and immunology. Thereby, I am focusing on following targets:

  • Melanin Concentrating Hormone Receptor 1 (MCHR1)
  • Glucose and fatty acid metabolism
  • ED-B Fibronectin
  • T-cells
  • Fibroblast Activation Protein (FAP)
  • Folate Receptor alpha (FRa)

My expertise rages from radiochemistry to non-invasive molecular imaging and ex vivo analyses.

Techniques, methods & infrastructure


  • Radiosynthesis
  • Binding-studies (cell culture)
  • Metabolism
  • Blood-brain-barrier penetration
  • Autoradiography
  • Immunhistochemistry
  • Small animal PET/CT/MRI
  • Biodistribution
  • Genotyping
  • PCR
  • MACS
  • FACS

 Access to the Preclinical Imaging Laboratory (FELASA certificate).

Selected publications

  1. Philippe, C. et al. (2021) ‘Discovery of melanin‐concentrating hormone receptor 1 in brown adipose tissue’, Annals of the New York Academy of Sciences, 1494(1), pp. 70–86. Available at:
  2. Philippe, C. et al. (2018) ‘SNAPshots of the MCHR1: a Comparison Between the PET-Tracers [18F]FE@SNAP and [11C]SNAP-7941’, Molecular Imaging and Biology, 21(2), pp. 257–268. Available at:
  3. Zeilinger, M. et al. (2017) ‘In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [11C]SNAP-7941 and [18F]FE@SNAP reveal specific uptake in the ventricular system’, Scientific Reports, 7(1). Available at:
  4. Balber, T. et al. (2019) ‘In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes’, Frontiers in Endocrinology, 10. Available at:
  5. Vraka, C. et al. (2022) ‘Simultaneous radiomethylation of [11C]harmine and [11C]DASB and kinetic modeling approach for serotonergic brain imaging in the same individual’, Scientific Reports, 12(1). Available at: