Univ.-Prof. Mag. Dr. Martin POSCH

Center for Medical Statistics, Informatics, and Intelligent Systems
(Section for Medical Statistics)

Email: martin.posch@meduniwien.ac.at

Research Interests
Group sequential trials, adaptive designs and multiple testing, focusing on applications in clinical trials and Bioinformatics

Selected Publications

F Ehmann, M Papaluca Amati, T Salmonson, M Posch, S Vamvakas, R Hemmings, H G Eichler and C K Schneider. Gatekeepers and Enablers: How Drug Regulators Respond to a Challenging and Changing Environment by Moving Toward a Proactive Attitude. Clinical Pharmacology & Therapeutics (2013)  doi:10.1038/clpt.2013.14
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Posch M and Bauer P. Adaptive Budgets in Clinical Trials. Statistics in Biopharmaceutical Research, to appear, 2013

Marshall S F, R Hemmings, F Josephson, M O Karlsson, M Posch and J-L Steimer. Modeling and Simulation to Optimize the Design and Analysis of Confirmatory Trials, Characterize Risk–Benefit, and Support Label Claims. CPT: Pharmacometrics & Systems Pharmacology, 2, e27; doi:10.1038/psp.2013.4 (2013)

Posch M, Proschan MA. Unplanned adaptations before breaking the blind. Stat Med. 2012, doi: 10.1002/sim.5361.

Zehetmayer S, Posch M. False discovery rate control in two-stage designs. BMC Bioinformatics. 2012 May 6;13(1):81.

Brenda G, Koch A, Miller F, Posch M, Vandemeulebroecke M, Wang SJ. Perspective on adaptive designs: 4 years European Medicines Agency reflection paper, 1 year draft US FDA guidance - where are we now? Clinical Investigation, 2:235-240 (2012)