Comprehensive Center for Pediatrics, Department of Pediatrics and Adolescent Medicine (Clinical Division of Pediatric Nephrology and Gastroenterology)
Position: Research Associate (Postdoc)
ORCID: 0000-0003-1946-7770
T +43 1 40400 73815
rebecca.herzog@meduniwien.ac.at
Keywords
Animal models; Carbohydrate Metabolism; Inflammation; Metabolomics; Nephrology; Peritoneal Dialysis; Proteomics; Randomized Controlled Trial
Research group(s)
Techniques, methods & infrastructure
In our CDL we use omics techniques (transcriptomics, proteomics, metabolomics, microbiome) to characterize molecular profiles of clinical samples and samples obtained from in-vitro and in-vivo models, using previously established bioinformatic tools as well as novel analytical approaches (high abundance protein depletion/low abundance protein enrichment approach, etc.)
Grants
- Christian Doppler Laboratory for Peritoneal Regulation of the Immune-Metabolic Ecosystem in Peritoneal Dialysis (CDL-PRIME-PD) (2026)
Source of Funding: CDG (Christian Doppler Research Association), Christian Doppler Laboratory
Principal Investigator - InfraPET (2023)
Source of Funding: Vienna Business Agency, Innovation
Principal Investigator - PD3 - Proteome Analysis of Peritoneal Dialysis Cell Populations (2021)
Source of Funding: FWF (Austrian Science Fund), Elise-Richter / Senior-Postdoc-Programm
Principal Investigator - Identification and Management of Patients at Risk – Outcome and Vascular Events in Peritoneal Dialysis (IMPROVE-PD) (2018)
Source of Funding: EU, Horizon 2020 Marie Curie ITN
Principal Investigator
Selected publications
- Herzog, R. et al., 2021. Lithium preserves peritoneal membrane integrity by suppressing mesothelial cell αB-crystallin. Science Translational Medicine, 13(608). Available at: http://dx.doi.org/10.1126/scitranslmed.aaz9705.
- Bartosova, M. et al., 2021. Glucose Derivative Induced Vasculopathy in Children on Chronic Peritoneal Dialysis. Circulation Research, 129(5). Available at: http://dx.doi.org/10.1161/CIRCRESAHA.121.319310.
- Vychytil, A. et al., 2018. A randomized controlled trial of alanyl-glutamine supplementation in peritoneal dialysis fluid to assess impact on biomarkers of peritoneal health. Kidney International, 94(6), pp.1227–1237. Available at: http://dx.doi.org/10.1016/j.kint.2018.08.031.
- Herzog, R. et al., 2018. Effects of Alanyl-Glutamine Treatment on the Peritoneal Dialysis Effluent Proteome Reveal Pathomechanism-Associated Molecular Signatures. Molecular & Cellular Proteomics, 17(3), pp.516–532. Available at: http://dx.doi.org/10.1074/mcp.RA117.000186.
- Herzog, R. et al., 2014. DynamicO-LinkedN-Acetylglucosamine Modification of Proteins Affects Stress Responses and Survival of Mesothelial Cells Exposed to Peritoneal Dialysis Fluids. Journal of the American Society of Nephrology, 25(12), pp.2778–2788. Available at: http://dx.doi.org/10.1681/ASN.2013101128.