Department of Plastic, Reconstructive and Aesthetic Surgery
Position: Research Associate (Postdoc)
ORCID: 0000-0002-1461-6274
T +43 1 40400 41700
sarah.stadlmayr@meduniwien.ac.at
Keywords
Biomimetic Materials; Nerve Regeneration; Regenerative Medicine; Tissue Engineering
Research group(s)
- ARGE Radtke
Research Area: cell based therapies and spider silk conduits for peripheral nerve regeneration
Members:
Research interests
Within the scope of my research, I try to unravel the unique properties of spider silk responsible for its exceptional ability to support peripheral nerve regeneration. I combine methods such as mass spectrometry, electron microscopy, and atomic force microscopy, with in vitro studies to determine the crucial chemical, structural, and morphological properties of spider silk.
Techniques, methods & infrastructure
- Primary Rodent Cell Culture (Schwann Cells, Endothelial Cells, Fibroblasts,...)
- Live Cell Imaging
- Confocal Laser Scanning Microscopy
- Atomic Force Microscopy
- Nanoindentation
- Electron Microscopy
- Proteomics (nLC-nESI-MS/MS)
- Lipidomics (GC-MS)
- Transcriptomics (RNASeq, Microarray)
- Zeta Potential Measurements
- Wettability/ Contact Angle Measurements
Grants
- Functionalized Spider Silk Replica for Nerve Regeneration (2025)
Source of Funding: FWF (Austrian Science Fund), Erwin Schrödinger
Principal Investigator
Selected publications
- Stadlmayr, S. et al. (2024) ‘Holistic Analysis of Material Properties in Phylogenetically Diverse Spider Silks and Their Influence on Cell Adhesion’, Advanced Functional Materials [Preprint]. Available at: https://doi.org/10.1002/adfm.202415945.
- Stadlmayr, S. et al. (2023) ‘Comparative Analysis of Various Spider Silks in Regard to Nerve Regeneration: Material Properties and Schwann Cell Response’, Advanced Healthcare Materials, 13(8). Available at: https://doi.org/10.1002/adhm.202302968.
- Semmler, L. et al. (2023) ‘Silk‐in‐Silk Nerve Guidance Conduits Enhance Regeneration in a Rat Sciatic Nerve Injury Model’, Advanced Healthcare Materials, p. 2203237. Available at: http://dx.doi.org/10.1002/adhm.202203237.
- Naghilou, A. et al. (2023) ‘Insights into the material properties of dragline spider silk affecting Schwann cell migration’, International Journal of Biological Macromolecules, 244, p. 125398. Available at: https://doi.org/10.1016/j.ijbiomac.2023.125398.